What to Know About Taking Pregabalin (Lyrica)

Lyrica or Pregabalin - What to know about taking

Lyrica is a medication that can help control seizures and certain types of pain by decreasing the number of signals that damaged nerves send out. This can be useful for managing conditions like epilepsy, fibromyalgia, and various other conditions with similar neurological features. Lyrica’s generic name is “pregabalin,” and it is available in multiple dosage forms, including a capsule, an extended-release tablet, and as a solution.

Some people are allergic to pregabalin, so always be sure to discuss the signs of an allergic reaction with a doctor. There is also a potential for misuse with Lyrica and the drug may not be suitable for people with a history of drug misuse. However, at the typical doses, the risk of addiction is relatively low.

Understanding Pregabalin (Lyrica)

Pregabalin is an anticonvulsant, analgesic, and anxiolytic medication, meaning it can treat seizures, pain, and anxiety, respectively. In fact, because of its many effects, pregabalin can treat a range of conditions.

All forms of pregabalin, including Lyrica, are considered Schedule V drugs in the United States. This means that while there is the risk for misuse, the drug has a low abuse potential in comparison to other medications. Despite this, some people describe a feeling of elation—similar to the “high” from marijuana—while using pregabalin. Because of this, a doctor may feel that the drug is not a good fit for certain individuals, despite its overall safety and effectiveness.

Uses and Benefits of Pregabalin

The FDA originally approved pregabalin in 2004 as an anti-epileptic drug. By slowing down impulses in the brain that cause seizures, the medication makes conditions like epilepsy far more manageable; but that is not where pregabalin’s strengths end. The medication also affects chemicals in the brain that send pain signals through the nervous system. Because of this, the drug has since been approved to treat many different types of pain. Doctors prescribe it for the pain that follows shingles and pain from diabetic nerve damage, fibromyalgia, and spinal cord injuries.

Pregabalin is also prescribed for:

  • generalized anxiety disorder and social anxiety disorder
  • pre-operative anxiety before surgeries
  • post-traumatic stress disorder alongside other medications—as an off-label intervention

Risks and Side Effects

Overall, Lyrica and its generic form are quite safe, though there are still some side effects and risks to be mindful of. Over 10% of people experience dizziness or drowsiness while taking pregabalin.

Other minor side effects include:

  • Dry mouth
  • Headache
  • Gas, bloating, or similar issues
  • Sleepiness
  • Trouble concentrating
  • Weight gain

If the effects are relatively minor, they may go away on their own within a few days up to a couple of weeks. Should the side effects be more severe, speak with your doctor immediately.

One of the more dangerous risks of pregabalin is an allergic reaction. In some cases, the reaction may be life-threatening. Some symptoms indicating an allergy are:

  • Trouble breathing
  • Rash, hives, or blisters
  • Swelling of the face, lips, mouth, gums, tongue, neck, or throat
  • Swelling of the extremities
  • Wheezing

Beyond the allergic reactions, other severe Lyrica side effects that need immediate medical care include:

  • Blurry vision
  • Blisters
  • Chest pain
  • Extreme sleepiness
  • Fever
  • Thoughts of suicide or self-harm

Precautions and Considerations

If you know you are allergic to pregabalin, do not take the medication and tell your doctor and pharmacist. You should also alert them if you are allergic to any other medications. Some people are allergic to the ingredients in drug preparations. Ask your doctor for a list of ingredients to help avoid any reactions.

As with other medications, drug interactions can occur with pregabalin. Be sure to provide your healthcare team with all of the prescription and nonprescription medications you are taking, as well as any nutritional supplements, vitamins, and herbal products.

The effects of pregabalin during pregnancy or while breastfeeding are still unknown. Some studies indicate a potential for harm. Experts may advise avoiding the medication in these cases or if you are planning to become pregnant.

Because dizziness and drowsiness are such common side effects, do not drive or operate heavy machinery until you know how the drug affects you.

Pregabalin can affect a person’s mood, sometimes severely via suicidal ideation. Immediately contact your doctor if you notice a change in mood.

As a Schedule V drug, pregabalin doesn’t have the same risk of addiction as stronger medications, such as opioids. However, there is still a risk of addiction, especially if you take the drug over a long period.

Dosage and Administration

Lyrica is available as an oral capsule or solution, while Lyrica CR is an extended-release oral tablet. Generic pregabalin is also available in these three dosage forms.

Take Lyrica exactly as your doctor prescribes and follow all instructions on the prescription label, medication guide, or other informative sheets.

Take the medication at the same time every day, with or without food.

If you are taking an extended-release tablet, do not break, crush, or chew the tablet.

Do not stop using pregabalin suddenly. Always contact a doctor if you need to stop taking the medication for any reason.

Treatment Duration and Withdrawal

At the typical doses, the risk of addiction to Lyrica is low—but never zero. Many people take Lyrica for extended periods to treat various conditions. This can lead to dependency. This also means that withdrawal symptoms can occur if you abruptly stop taking pregabalin. Some of these symptoms can include anxiety, diarrhea, headache, insomnia, excessive sweating, nausea, major depression, pain, and seizures.

Final Words

Though pregabalin cannot cure any conditions, it can be a powerful tool in effectively managing conditions that are often very hard to live with, like epilepsy and fibromyalgia. As long as you remain aware of the risks and keep your doctor updated on any issues you’re experiencing, Lyrica and its generic forms can provide a significant amount of relief.

If you or someone you love is struggling with neurological pain or symptoms of fibromyalgia, epilepsy, or an anxiety disorder, pregabalin may be able to help. Restore Mental Health’s experts have extensive experience prescribing pregabalin for various conditions. Contact us online or call today.